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Article

Octamerization is essential for enzymatic function of human UDP-glucose pyrophosphorylase.

Glycobiology - 1 Apr 2013

Führing Jana, Damerow Sebastian, Fedorov Roman, Schneider Julia, Münster-Kühnel Anja-Katharina, Gerardy-Schahn Rita

Abstract excerpt

Uridine diphosphate-glucose pyrophosphorylase (UGP) occupies a central position in carbohydrate metabolism in all kingdoms of life, since its product uridine diphosphate-glucose (UDP-glucose) is essential in a number of anabolic and catabolic pathways and is a precursor for other sugar nucleotides. Its significance as a virulence factor in protists and bacteria has given momentum to the search for...

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PMID: 23254995
DOI: 10.1093/glycob/cws217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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