Article
Advanced systemic mastocytosis: the impact of KIT mutations in diagnosis, treatment, and progression.
European journal of haematology - 1 Feb 2013
Verstovsek Srdan
Abstract excerpt
Apart from indolent systemic mastocytosis (SM), which is associated with a favorable prognosis, other subtypes of SM (SM with associated clonal hematologic non-mast cell lineage disease, aggressive SM, and mast cell leukemia - collectively referred to in this review as advanced SM) can be debilitating. The complexity of SM makes both the diagnosis and design of response criteria challenging for clinical studies....
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