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Article

IDH-Mutation Is a Weak Predictor of Long-Term Survival in Glioblastoma Patients.

PloS one - 1 Jan 2015

Amelot Aymeric, De Cremoux Patricia, Quillien Véronique, Polivka Marc, Adle-Biassette Homa, Lehmann-Che Jacqueline, Françoise Laurence, Carpentier Antoine F, George Bernard, Mandonnet Emmanuel, Froelich Sébastien

Abstract excerpt

BACKGROUND: A very small proportion of patients diagnosed with glioblastoma (GBM) survive more than 3 years. Isocitrate dehydrogenase 1 or 2 (IDH1/2) mutations define a small subgroup of GBM patients with favourable prognosis. However, it remains controversial whether long-term survivors (LTS) are found among those IDH1/2 mutated patients. METHODS: We retrospectively analyzed 207 GBM patients followed at...

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Source

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Identifiers

PMID: 26158269
DOI: 10.1371/journal.pone.0130596
PMCID: PMC4497660

Genes

IDH1
IDH2
MGMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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