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Article

Do Long-Term Survivor Primary Glioblastoma Patients Harbor IDH1 Mutations?

Journal of neurological surgery. Part A, Central European neurosurgery - 1 May 2016

Sarmiento J Manuel, Mukherjee Debraj, Black Keith L, Fan Xuemo, Hu Jethro L, Nuno Miriam Aracely, Patil Chirag G

Abstract excerpt

BACKGROUND: Approximately 3 to 16% of glioblastoma multiforme (GBM) patients are considered long-term survivors (LTS: 3+ years). OBJECTIVE: Given the improved survival conferred by IDH1 mutations and the fact that these mutations are detected in 12% of newly diagnosed GBM cases, could long-term survivorship be explained by IDH1 mutation status? Our aim was to describe GBM LTS with IDH1 mutations and explore its...

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Brain Neoplasms
Disease-Free Survival
Genetic Association Studies
Glioblastoma
Isocitrate Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26935296
DOI: 10.1055/s-0035-1566121

Genes

IDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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