Article
Do Long-Term Survivor Primary Glioblastoma Patients Harbor IDH1 Mutations?
Journal of neurological surgery. Part A, Central European neurosurgery - 1 May 2016
Sarmiento J Manuel, Mukherjee Debraj, Black Keith L, Fan Xuemo, Hu Jethro L, Nuno Miriam Aracely, Patil Chirag G
Abstract excerpt
BACKGROUND: Approximately 3 to 16% of glioblastoma multiforme (GBM) patients are considered long-term survivors (LTS: 3+ years). OBJECTIVE: Given the improved survival conferred by IDH1 mutations and the fact that these mutations are detected in 12% of newly diagnosed GBM cases, could long-term survivorship be explained by IDH1 mutation status? Our aim was to describe GBM LTS with IDH1 mutations and explore its...
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