Article
Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling.
International journal of cancer - 15 Oct 2014
Reifenberger Guido, Weber Ruthild G, Riehmer Vera, Kaulich Kerstin, Willscher Edith, Wirth Henry, Gietzelt Jens, Hentschel Bettina, Westphal Manfred, Simon Matthias, Schackert Gabriele, Schramm Johannes, Matschke Jakob, Sabel Michael C, Gramatzki Dorothee, Felsberg Jörg, Hartmann Christian, Steinbach Joachim P, Schlegel Uwe, Wick Wolfgang, Radlwimmer Bernhard, Pietsch Torsten, Tonn Jörg C, von Deimling Andreas, Binder Hans, Weller Michael, Loeffler Markus
Abstract excerpt
The prognosis of glioblastoma, the most malignant type of glioma, is still poor, with only a minority of patients showing long-term survival of more than three years after diagnosis. To elucidate the molecular aberrations in glioblastomas of long-term survivors, we performed genome- and/or transcriptome-wide molecular profiling of glioblastoma samples from 94 patients, including 28 long-term survivors with >36...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
