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Article

MMP9 Promoter Polymorphism (-1562 C/T) Does not Affect the Serum Levels of Soluble MICB and MICA in Breast Cancer.

Iranian journal of immunology : IJI - 1 Mar 2016

Bargostavan Mohammad Hasan, Eslami Gilda, Esfandiari Nasrin, Shams Shahemabadi Ali

Abstract excerpt

BACKGROUND: The role of Matrix Metalloproteinase 9 (MMP9) in tumor invasion and progression is prominent. A single nucleotide polymorphism (SNP) in the promoter region of MMP9 (-1562 C/T) increases the transcription and expression of this gene. On the other hand, MHC class I chain-related protein A and B (MICA/B) in soluble forms may impair tumor immunogenicity by reducing Natural Killer Group 2D (NKG2D)...

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Source

Identifiers

PMID: 27026046
DOI: 10.22034/iji.2016.16727

Genes

MICA
MMP9
MICB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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