The association between MTHFR 677C>T polymorphism and cervical cancer: evidence from a meta-analysis.

doi:10.1186/1471-2407-12-467

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Article

The association between MTHFR 677C>T polymorphism and cervical cancer: evidence from a meta-analysis.

BMC cancer - 11 Oct 2012

Mei Qiang, Zhou Daijun, Gao Jinyu, Shen Shu, Wu Jinlin, Guo Linna, Liang Zhiqing

Abstract excerpt

BACKGROUND: MTHFR 677C>T polymorphism is a genetic alteration in an enzyme involved in folate metabolism, but its effect on host susceptibility to cervical cancer is still uncertain. The aim of this study was to investigate the association between MTHFR 677C>T polymorphism and cervical cancer by performing a meta-analysis. METHODS: Pubmed, Embase, Web of Science, and the Chinese Biomedical Database (CBM)...

Topics

Female
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Neoplasm Proteins
Polymorphism, Single Nucleotide
Uterine Cervical Neoplasms

Source

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Identifiers

PMID: 23057736
DOI: 10.1186/1471-2407-12-467
PMCID: PMC3583684

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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