Article
Cell periphery-related proteins as major genomic targets behind the adaptive evolution of an industrial Saccharomyces cerevisiae strain to combined heat and hydrolysate stress.
BMC genomics - 9 Jul 2015
Wallace-Salinas Valeria, Brink Daniel P, Ahrén Dag, Gorwa-Grauslund Marie F
Abstract excerpt
BACKGROUND: Laboratory evolution is an important tool for developing robust yeast strains for bioethanol production since the biological basis behind combined tolerance requires complex alterations whose proper regulation is difficult to achieve by rational metabolic engineering. Previously, we reported on the evolved industrial Saccharomyces cerevisiae strain ISO12 that had acquired improved tolerance to grow...
Topics
- Biological Evolution
- Ethanol
- Genomics
- Hot Temperature
- Industrial Microbiology
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Selection, Genetic
- Sequence Analysis, DNA