Sporulation generates stress-dependent phenotypic variability in the heterothallic industrial Saccharomyces cerevisiae Ethanol Red.

doi:10.1038/s41598-026-56263-5

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Article

Sporulation generates stress-dependent phenotypic variability in the heterothallic industrial Saccharomyces cerevisiae Ethanol Red.

Scientific reports - 13 Jun 2026

Paulon Viviana, Gupte Ameya Pankaj, Stojkov Katarina, Ruspi Chiara, Casagrande Pierantoni Debora, Basaglia Marina, Cardinali Gianluigi, Favaro Lorenzo, Corte Laura

Abstract excerpt

The industrial yeast Saccharomyces cerevisiae Ethanol Red is widely used in large-scale bioethanol production and is generally considered phenotypically stable because of its heterothallic diploid background. Here, we investigated whether extensive sporulation of this highly domesticated strain could generate functional diversification without genetic engineering. Thirty monosporal cultures (MSCs) were randomly...

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PMID: 42288572
DOI: 10.1038/s41598-026-56263-5
PMCID: PMC13522619

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