Article
The clinical utility of molecular genetic cancer profiling.
Expert review of molecular diagnostics - 1 Aug 2016
Joseph Loren
Abstract excerpt
INTRODUCTION: Next-Generation-Sequencing (NGS) has enabled gene mutation profiling - cataloguing sequence variants and modifications in clinical assays encompassing tens to thousands of genes in tumors and in germlines. The clinical benefit of applying multi-gene NGS to diverse applications in various malignancies remains to be demonstrated. AREAS COVERED: Applications of gene mutation profiling in oncology...
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