Article
The Relationship between Runs of Homozygosity and Inbreeding in Jersey Cattle under Selection.
PloS one - 1 Jan 2015
Kim Eui-Soo, Sonstegard Tad S, Van Tassell Curtis P, Wiggans George, Rothschild Max F
Abstract excerpt
Inbreeding is often an inevitable outcome of strong directional artificial selection but on average it reduces population fitness with increased frequency of recessive deleterious alleles. Runs of homozygosity (ROH) representing genomic autozygosity that occur from mating between selected and genomically related individuals may be able to reveal the regions affecting fitness. To examine the influence of genomic...
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