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Article

Identification of genomic regions associated with inbreeding depression in Holstein and Jersey dairy cattle.

Genetics, selection, evolution : GSE - 18 Nov 2014

Pryce Jennie E, Haile-Mariam Mekonnen, Goddard Michael E, Hayes Ben J

Abstract excerpt

BACKGROUND: Inbreeding reduces the fitness of individuals by increasing the frequency of homozygous deleterious recessive alleles. Some insight into the genetic architecture of fitness, and other complex traits, can be gained by using single nucleotide polymorphism (SNP) data to identify regions of the genome which lead to reduction in performance when identical by descent (IBD). Here, we compared the effect of...

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Identifiers

PMID: 25407532
DOI: 10.1186/s12711-014-0071-7
PMCID: PMC4234836

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