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Article

Quasispecies analysis and in vitro susceptibility of HBV strains isolated from HIV-HBV-coinfected patients with delayed response to tenofovir.

Antiviral therapy - 1 Jan 2012

Lada Olivier, Gervais Anne, Branger Michel, Peytavin Gilles, Roquebert Benedicte, Collin Gilles, Fraqueiro Gil, Moucari Rami, Leclerc Laurence, Martinot-Peignoux Michelle, Matheron Sophie, Marcellin Patrick

Abstract excerpt

BACKGROUND: Among 141 HIV-HBV-coinfected patients treated with tenofovir in our centre, 87% were good-responders to therapy. Seven patients showed a delayed response to tenofovir. The present study was performed to evaluate the quasispecies variability and the in vitro drug susceptibility to approved antiviral drugs of HBV genomes directly isolated from patients' sera. METHODS: After purification of DNA from...

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PMID: 22267470
DOI: 10.3851/IMP1940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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