Article
Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers.
BMC cancer - 8 Jul 2015
Yan Max, Shield-Artin Kristy, Byrne David, Deb Siddhartha, Waddell Nic, Haviv Izhak, Fox Stephen B
Abstract excerpt
BACKGROUND: While a number of studies have examined miRNA profiles across the molecular subtypes of breast cancer, it is unclear whether BRCA1 basal-like cancers have a specific miRNA profile. This study aims to compare grade independent miRNA expression in luminal cancers, sporadic and BRCA1 basal-type breast cancers. It also aims to ascertain an immunohistochemical profile regulated by BRCA1 specific miRNAs for...
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