Article
Clinical and pathologic aspects of basal-like breast cancers.
Nature clinical practice. Oncology - 1 Mar 2008
Fadare Oluwole, Tavassoli Fattaneh A
Abstract excerpt
Gene-expression profiling of breast cancers has shown that distinct molecular subclasses are present within tumors that are apparently morphologically similar. The molecular subclasses of cohorts classified by the 'intrinsic' gene set include the luminal A and B, erbB-2+, normal-breast-like, and basal-like tumors. Basal-like breast cancers have been reported to be associated with worse overall and disease-free...
Topics
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Female
- Gene Expression Profiling
- Genes, BRCA1
- Germ-Line Mutation
- Humans
- Neoplasm Invasiveness
- Neoplasms, Basal Cell
- Phenotype
- Prognosis