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Article

Manipulating megakaryocytes to manufacture platelets ex vivo.

Journal of thrombosis and haemostasis : JTH - 1 Jun 2015

Karagiannis P, Eto K

Abstract excerpt

Historically, platelet transfusion has proven a reliable way to treat patients suffering from thrombocytopenia or similar ailments. An undersupply of donors, however, has demanded alternative platelet sources. Scientists have therefore sought to recapitulate the biological events that convert hematopoietic stem cells into platelets in the laboratory. Such platelets have shown good function and potential for...

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Identifiers

PMID: 26149050
DOI: 10.1111/jth.12946
PMCID: PMC4501322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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