Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Road blocks in making platelets for transfusion.

Journal of thrombosis and haemostasis : JTH - 1 Jun 2015

Thon J N, Medvetz D A, Karlsson S M, Italiano J E

Abstract excerpt

The production of laboratory-generated human platelets is necessary to meet present and future transfusion needs. This manuscript will identify and define the major roadblocks that must be overcome to make human platelet production possible for clinical use, and propose solutions necessary to accelerate development of laboratory-generated human platelets to market.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioreactors
Share to Blood Platelets
Share to Cell Culture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cellular Reprogramming

Share to Megakaryocytes

Share to Platelet Transfusion

Share to Stem Cell Niche

Share to Thrombopoiesis

Source

Open in PubMed Open full text

Identifiers

PMID: 26149051
DOI: 10.1111/jth.12942
PMCID: PMC5565795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Road blocks in making platelets for transfusion.PMID 26149051Read ↗

Ex vivo manufacturing of platelets: beyond the first-in-human clinical trial using autologous iPSC-plateletsSemantic proximity Read ↗

Platelet production from induced pluripotent stem cells.Semantic proximity Read ↗

Manipulating megakaryocytes to manufacture platelets ex vivo.Semantic proximity Read ↗

Translational approaches to functional platelet production ex vivo.Semantic proximity Read ↗

Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem CellsSemantic proximity Read ↗

Platelet dysfunction reversal with cold-stored vs. room temperature-stored platelet transfusionsSemantic proximity Read ↗

Quality Validation of Platelets Obtained From the Haemonetics and Trima Accelautomated Blood-collection SystemsSemantic proximity Read ↗

Induced Pluripotent Stem Cell-Derived Megakaryocytes and Platelets for Disease Modeling and Future Clinical Applications.Semantic proximity Read ↗

Gaps in the knowledge of human platelet lysate as a cell culture supplement for cell therapy: a joint publication from the AABB and the International Society for Cell & Gene TherapySemantic proximity Read ↗

Gaps in the knowledge of human platelet lysate as a cell culture supplement for cell therapy: a joint publication from the AABB and the International Society for Cell & Gene TherapySemantic proximity Read ↗

Towards the standardization of human platelet lysate production and its comparison to fetal bovine serum for human hematopoietic cell culture: a scoping reviewSemantic proximity Read ↗

Platelet-derived microparticles analysis: Techniques, challenges and recommendationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.