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Article

Involvement of Acidic Amino Acid Residues in Zn(2+) Binding to Respiratory Complex I.

Chembiochem : a European journal of chemical biology - 21 Sept 2015

Kriegel Sébastien, Srour Batoul, Steimle Stefan, Friedrich Thorsten, Hellwig Petra

Abstract excerpt

Proton transfer across membranes and membrane proteins is a central process in biological systems. Zn(2+) ions are capable of binding to acidic residues, often found within such specific pathways, thereby leading to a blockage. Here we probed Zn(2+) inhibition of the proton-pumping NADH:ubiquinone oxidoreductase from Escherichia coli by means of electrochemically induced FTIR difference spectroscopy. Numerous...

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PMID: 26147723
DOI: 10.1002/cbic.201500273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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