Article
The Redox-Bohr group associated with iron-sulfur cluster N2 of complex I.
The Journal of biological chemistry - 11 Aug 2006
Zwicker Klaus, Galkin Alexander, Dröse Stefan, Grgic Ljuban, Kerscher Stefan, Brandt Ulrich
Abstract excerpt
Proton pumping respiratory complex I (NADH:ubiquinone oxidoreductase) is a major component of the oxidative phosphorylation system in mitochondria and many bacteria. In mammalian cells it provides 40% of the proton motive force needed to make ATP. Defects in this giant and most complicated membrane-bound enzyme cause numerous human disorders. Yet the mechanism of complex I is still elusive. A group exhibiting...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
