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Article

Exploring the inhibitor binding pocket of respiratory complex I.

Biochimica et biophysica acta - 1 Jan 2000

Fendel Uta, Tocilescu Maja A, Kerscher Stefan, Brandt Ulrich

Abstract excerpt

Numerous hydrophobic and amphipathic compounds including several detergents are known to inhibit the ubiquinone reductase reaction of respiratory chain complex I (proton pumping NADH:ubiquinone oxidoreductase). Guided by the X-ray structure of the peripheral arm of complex I from Thermus thermoph...

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PMID: 18486594
DOI: 10.1016/j.bbabio.2008.04.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18486594-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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