Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Severe tricuspid regurgitation is a congestion-driven cardiorenal disease: A longitudinal study defining a right heart failure phenotype.

International journal of cardiology - 15 Oct 2026

Mansour Layal, Rasmeehirun Prayuth, L'Official Guillaume, Marut Benjamin, Lacout Marion, Bezard Melanie, Donal Erwan

Abstract excerpt

BACKGROUND: Severe tricuspid regurgitation (TR) is increasingly recognized as a major determinant of outcomes, yet its mechanistic trajectory under contemporary medical therapy remains insufficiently defined. OBJECTIVES: To characterize the longitudinal evolution of severe TR managed conservatively and to define a reproducible congestion-right ventricle-renal phenotype associated with clinical outcomes. METHODS:...

Topics

Join the communities discussing this publication.

Aged
Aged, 80 and over
Cohort Studies
Follow-Up Studies
Heart Failure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Longitudinal Studies

Severity of Illness Index

Source

Identifiers

PMID: 42392510
DOI: 10.1016/j.ijcard.2026.134643

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Severe tricuspid regurgitation is a congestion-driven cardiorenal disease: A longitudinal study defining a right heart failure phenotype.PMID 42392510Read ↗

Hemodynamic and Metabolic-Inflammatory Phenotyping Across the Cardiac Index Spectrum in Moderate and Severe Tricuspid Regurgitation: Prognostic Implications.Semantic proximity Read ↗

Canadian Cardiovascular Society-Canadian Heart Failure Society Focused Clinical Practice Update of Patients With Differing Heart Failure Phenotypes.Semantic proximity Read ↗

Patient phenotype profiling using echocardiography and natriuretic peptides to personalise heart failure therapy.Semantic proximity Read ↗

Clinical phenotypes according to diuretic combination in acute heart failure.Semantic proximity Read ↗

Gender differences in clinical phenotype, right-heart remodelling and outcomes in severe tricuspid regurgitation: a cardiac magnetic resonance study.Semantic proximity Read ↗

Left ventricular heart failure and pulmonary hypertension.Semantic proximity Read ↗

Tricuspid valve regurgitation accelerates heart failure via a cardio-intestinal innate immune circuitSemantic proximity Read ↗

Right Heart Phenotype in Heart Failure With Preserved Ejection Fraction.Semantic proximity Read ↗

The congestion “Pandemic” in Acute Heart Failure PatientsSemantic proximity Read ↗

Heart failure with non-reduced ejection fraction: Epidemiology, pathophysiology, phenotypes, diagnosis and treatment approaches.Semantic proximity Read ↗

Phenotyping of Fontan-Associated Renal Physiology and Disease.Semantic proximity Read ↗

Influence of renal dysfunction phenotype on mortality in the setting of cardiac dysfunction: analysis of three randomized controlled trials.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.