Article
Accelerated Aging Fontan Phenotype Is Associated With Systemic Right Ventricles and Adverse Hemodynamics.
Journal of the American Heart Association - 15 Sept 2026
Woo Jennifer P, Vincent Annabelle Grace Binti, Kushwaha Ankit, Gan Sushrima, Ichimura Shoko, Egorova Anastasia D, Veldtman Gruschen R, Wyss-Coray Tony, Le Guen Yann, Reddy Sushma
Abstract excerpt
BACKGROUND: Accelerated biological aging occurs when biological age outpaces chronological age. Congenital heart disease is associated with an increased risk for age-related diseases. The role of biological aging in individuals with the most severe forms of congenital heart disease, those with a Fontan circulation, is not known. METHODS: In this case-control study, we compared the telomere lengths of patients...
Read the complete abstract on PubMedTopics
- Humans
- Fontan Procedure
- Female
- Phenotype
- Heart Defects, Congenital
- Male