Article
The Complex Type 2 Endotype in Allergy and Asthma: From Laboratory to Bedside.
Current allergy and asthma reports - 1 Jun 2015
Agache Ioana, Sugita Kazunari, Morita Hideaki, Akdis Mübeccel, Akdis Cezmi A
Abstract excerpt
Better management of allergic diseases needs a sharpened understanding of disease heterogeneity and mechanisms in relation to clinically significant outcomes. Phenotypes describing observable clinical and morphologic characteristics and unique responses to treatment have been developed; however, they do not relate to disease mechanisms. Recently, extended heterogeneous and disease-related metabolic, inflammatory,...
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