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Article

New concepts in asthma: clinical phenotypes and pathophysiological mechanisms.

Drug discovery today - 1 Feb 2017

Koczulla Andreas R, Vogelmeier Claus F, Garn Holger, Renz Harald

Abstract excerpt

Asthma is among the most common chronic inflammatory diseases worldwide. Recent evidence indicates that the pathogenesis shows a high degree of heterogeneity. Patient subsets have been identified that exhibit different cellular and molecular patterns of dysregulation. A prominent example is eosinophilic Th2-driven asthma. These unique and molecular patterns are termed endotypes. Characterization of endotypes has...

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Identifiers

PMID: 27867084
DOI: 10.1016/j.drudis.2016.11.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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