Article
Resolving Clinical Phenotypes into Endotypes in Allergy: Molecular and Omics Approaches.
Clinical reviews in allergy & immunology - 1 Apr 2021
Mersha Tesfaye B, Afanador Yashira, Johansson Elisabet, Proper Steven P, Bernstein Jonathan A, Rothenberg Marc E, Khurana Hershey Gurjit K
Abstract excerpt
Allergic diseases are highly complex with respect to pathogenesis, inflammation, and response to treatment. Current efforts for allergic disease diagnosis have focused on clinical evidence as a binary outcome. Although outcome status based on clinical phenotypes (observable characteristics) is convenient and inexpensive to measure in large studies, it does not adequately provide insight into the complex molecular...
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