Article
Understanding Asthma Phenotypes, Endotypes, and Mechanisms of Disease.
Clinical reviews in allergy & immunology - 1 Apr 2019
Kuruvilla Merin E, Lee F Eun-Hyung, Lee Gerald B
Abstract excerpt
The model of asthma as a single entity has now been replaced by a much more complex biological network of distinct and interrelating inflammatory pathways. The term asthma is now considered an umbrella diagnosis for several diseases with distinct mechanistic pathways (endotypes) and variable clinical presentations (phenotypes). The precise definition of these endotypes is central to asthma management due to...
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