Article
Peripheral blood-derived cytokine gene polymorphisms and metabolic profile in women with polycystic ovary syndrome.
Cytokine - 1 Dec 2015
Sóter Mirelle O, Ferreira Cláudia N, Sales Mariana F, Candido Ana L, Reis Fernando M, Milagres Kátia S, Ronda Carla, Silva Ieda O, Sousa Marinez O, Gomes Karina B
Abstract excerpt
BACKGROUND: The imbalance between proinflammatory and anti-inflammatory pathways plays a role in polycystic ovary syndrome (PCOS) etiology. We aimed to investigate the relationship between polymorphisms of genes encoding inflammation-associated cytokines and the metabolic profile of Brazilian women with PCOS. DESIGN: Case-control study. METHODS: The study included 196 women - 97 with PCOS (diagnosed based on...
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