Cytokine gene polymorphisms in populations from Parana, Southern Brazil.

doi:10.1016/j.humimm.2017.03.011

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Cytokine gene polymorphisms in populations from Parana, Southern Brazil.

Human immunology - 1 Jan 2000

Reis Pâmela Guimarães, de Alencar Josiane Bazzo, Macedo Luciana Conci, Ambrosio-Albuquerque Eliane Papa, de Aquino Julimary Suematsu, Zacarias Joana Maira Valentini, Tsuneto Patrícia Yumeko, Moliterno Ricardo Alberto, Sell Ana Maria, Visentainer Jeane Eliete Laguila

Abstract excerpt

In this study, were genotyped 22 single nucleotide polymorphisms (SNPs) in 13 genes that encode the pro-inflammatory (IL-1α, IL-1β, IL-1R, IL-4Rα, IL-12, IFN-γ, TNF-α, and IL-2) and anti-inflammatory (IL-1RA, TGF-β, IL-4, IL-6 and IL-10) cytokines of 350 individuals by PCR-SSP (polymerase chain reaction - sequence specific primer). A total of 473 individuals were genotyped for IL17A and IL17F genes by PCR-RFLP...

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PMID: 28347702
DOI: 10.1016/j.humimm.2017.03.011

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