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Article

Tumor necrosis factor alpha (-308), interleukin-6 (-174) and interleukin-10 (-1082) gene polymorphisms in polycystic ovary syndrome.

European journal of obstetrics, gynecology, and reproductive biology - 1 May 2010

Vural Pervin, Değirmencioğlu Sevgin, Saral Neslihan Y, Akgül Cemil

Abstract excerpt

OBJECTIVE: The imbalance between pro- and anti-inflammatory cytokines and polymorphism of cytokine genes may play a role in the etiology of the polycystic ovary syndrome (PCOS). The aim of this study was to investigate the association of polymorphisms of TNFalpha, IL-6 and IL-10 genes with the occurrence and the clinical/laboratory characteristics of PCOS in the Turkish population. STUDY DESIGN: Single nucleotide...

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Adolescent
Gene Frequency
Interleukin-10
Interleukin-6
Polycystic Ovary Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 20189706
DOI: 10.1016/j.ejogrb.2010.02.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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