Article
Severe preeclampsia: association of genes polymorphisms and maternal cytokines production in Brazilian population.
Cytokine - 1 Feb 2015
Pinheiro Melina B, Gomes Karina B, Ronda Carla R S C, Guimarães Gabrielle G, Freitas Letícia G, Teixeira-Carvalho Andréa, Martins-Filho Olindo Assis, Dusse Luci M
Abstract excerpt
INTRODUCTION: Preeclampsia (PE) is a multi-system disorder of pregnancy characterized by hypertension and proteinuria. Healthy pregnancy is associated with a controlled inflammatory process, which is exacerbated in PE in response to excessive placental stimuli. Gene expression levels can affect inflammation and immune regulation. It is known that differences in cytokine allele frequencies amongst populations may...
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