Article
IL-6, TNF-α, and IL-10 levels/polymorphisms and their association with type 2 diabetes mellitus and obesity in Brazilian individuals.
Archives of endocrinology and metabolism - 1 Jan 2000
Rodrigues Kathryna Fontana, Pietrani Nathalia Teixeira, Bosco Adriana Aparecida, Campos Fernanda Magalhães Freire, Sandrim Valéria Cristina, Gomes Karina Braga
Abstract excerpt
OBJECTIVE: This study aimed to investigate the association of plasma TNF-α, IL-6, and lL-10 levels and cytokine gene polymorphisms [TNF-α (-308 G→A), IL-6 (-174 C→G) and IL-10 (-1082 A→G, -819 T→C and -592 A→C)] in type 2 diabetes mellitus (T2DM) and obese patients. SUBJECTS AND METHODS: One hundred and two T2DM patients and 62 controls were included in this study. Cytokine plasma levels were measured by the...
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