Article
Low Copy Number of the AMY1 Locus Is Associated with Early-Onset Female Obesity in Finland.
PloS one - 1 Jan 2015
Viljakainen Heli, Andersson-Assarsson Johanna C, Armenio Miriam, Pekkinen Minna, Pettersson Maria, Valta Helena, Lipsanen-Nyman Marita, Mäkitie Outi, Lindstrand Anna
Abstract excerpt
BACKGROUND: The salivary α-amylase locus (AMY1) is located in a highly polymorphic multi allelic copy number variable chromosomal region. A recent report identified an association between AMY1 copy numbers and BMI in common obesity. The present study investigated the relationship between AMY1 copy number, BMI and serum amylase in childhood-onset obesity. PATIENTS: Sixty-one subjects with a history of...
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