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Copy Number Polymorphism of the Salivary Amylase Gene: Implications in Human Nutrition Research

1 Jan 2012

Abstract excerpt

The salivary α-amylase is a calcium-binding enzyme that initiates starch digestion in the oral cavity. The α-amylase genes are located in a cluster on the chromosome that includes salivary amylase genes (AMY1), two pancreatic α-amylase genes (AMY2A and AMY2B) and a related pseudogene. The AMY1 genes show extensive copy number variation which is directly proportional to the salivary α-amylase content in saliva....

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PMID: 22965187
DOI: 10.1159/000339951

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