Article
Beneficial effect of a high number of copies of salivary amylase AMY1 gene on obesity risk in Mexican children.
Diabetologia - 1 Feb 2015
Mejía-Benítez María A, Bonnefond Amélie, Yengo Loïc, Huyvaert Marlène, Dechaume Aurélie, Peralta-Romero Jesús, Klünder-Klünder Miguel, García Mena Jaime, El-Sayed Moustafa Julia S, Falchi Mario, Cruz Miguel, Froguel Philippe
Abstract excerpt
AIMS/HYPOTHESIS: Childhood obesity is a major public health problem in Mexico, affecting one in every three children. Genome-wide association studies identified genetic variants associated with childhood obesity, but a large missing heritability remains to be elucidated. We have recently shown a strong association between a highly polymorphic copy number variant encompassing the salivary amylase gene (AMY1 also...
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