Characterization of Streptococcus pyogenes isolates from French children: emm-1 genotype is associated with invasive infections and spread of the M1UK clone.

doi:10.1093/jpids/piag006

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Article

Characterization of Streptococcus pyogenes isolates from French children: emm-1 genotype is associated with invasive infections and spread of the M1UK clone.

Journal of the Pediatric Infectious Diseases Society - 3 Feb 2026

Bidet Philippe, Giolito Anna, Levy Corinne, Cohen Robert, Bourmaud Aurélie, Pages Justine, Banini-Soussan Valérie, Chalumeau Martin, De Pontual Loic, Dubos François, Duval-Arnould Marc, Gajdos Vincent, Gillet Yves, Gras-Leguen Christèle, Grimprel Emmanuel, Lorrot Mathie, Haas Hervé, Hau Isabelle, Hees Laure, Hankard Régis, Maakaroun-Vermesse Zoha, Minodier Philippe, Toubiana Julie, Richer Olivier, Thollot Franck, Wollner Alain, Bonacorsi Stéphane, Picard Capucine, Faye Albert, Gaschignard Jean

Abstract excerpt

BACKGROUND: The bacterial determinants of Group A Streptococcus (GAS) associated with either invasive (IGASI) or non-invasive (NIGASI) infections remain controversial. METHODS: From 2014 to 2018, French children hospitalized for an IGASI were enrolled in a prospective multicenter study aimed at identifying bacterial virulence factors and predisposing immunologic and genetic factors. During the same period, age-...

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PMID: 41626762
DOI: 10.1093/jpids/piag006

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