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Article

Fibroblast viability and phenotypic changes within glycated stiffened three-dimensional collagen matrices.

Respiratory research - 1 Jul 2015

Vicens-Zygmunt Vanesa, Estany Susanna, Colom Adai, Montes-Worboys Ana, Machahua Carlos, Sanabria Andrea Juliana, Llatjos Roger, Escobar Ignacio, Manresa Frederic, Dorca Jordi, Navajas Daniel, Alcaraz Jordi, Molina-Molina Maria

Abstract excerpt

BACKGROUND: There is growing interest in the development of cell culture assays that enable the rigidity of the extracellular matrix to be increased. A promising approach is based on three-dimensional collagen type I matrices that are stiffened by cross-linking through non-enzymatic glycation with reducing sugars. METHODS: The present study evaluated the biomechanical changes in the non-enzymatically glycated...

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Source

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Identifiers

PMID: 26126411
DOI: 10.1186/s12931-015-0237-z
PMCID: PMC4494165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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