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Preparation of Extracellular Matrices Produced by Cultured and Primary Fibroblasts

1 Dec 2006

Abstract excerpt

Fibroblasts secrete and organize extracellular matrix (ECM), which provides structural support for their adhesion, migration, and tissue organization, besides regulating cellular functions such as growth and survival. Cell-to-matrix interactions are vital for vertebrate development. Disorders in these processes have been associated with fibrosis, developmental malformations, cancer, and other diseases. This unit...

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PMID: 18228495
DOI: 10.1002/0471143030.cb1009s33

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