Article
Glycated Collagen Stimulates Differentiation of Gingival Myofibroblasts.
Journal of periodontology - 1 Sept 2017
Retamal Ignacio N, Hernández Romina, Melo Francisco, Zapata Paulina, Martínez Constanza, Martínez Jorge, Smith Patricio C
Abstract excerpt
BACKGROUND: Glucose-derived metabolites may alter the structure and biologic properties of important proteins in periodontium, such as collagens. As a consequence, it is possible that collagen-binding cells may change their phenotypic traits. Although the glucose-derived product methylglyoxal (MGO) has been detected in periodontal lesions, the precise effect of collagen glycation on gingival connective tissue...
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