Glycated Collagen Stimulates Differentiation of Gingival Myofibroblasts.

doi:10.1902/jop.2017.160730

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Article

Glycated Collagen Stimulates Differentiation of Gingival Myofibroblasts.

Journal of periodontology - 1 Sept 2017

Retamal Ignacio N, Hernández Romina, Melo Francisco, Zapata Paulina, Martínez Constanza, Martínez Jorge, Smith Patricio C

Abstract excerpt

BACKGROUND: Glucose-derived metabolites may alter the structure and biologic properties of important proteins in periodontium, such as collagens. As a consequence, it is possible that collagen-binding cells may change their phenotypic traits. Although the glucose-derived product methylglyoxal (MGO) has been detected in periodontal lesions, the precise effect of collagen glycation on gingival connective tissue...

Topics

Actins
Apoptosis
Biomarkers
Cell Differentiation
Cell Survival
Cells, Cultured
Collagen
Fibronectins
Gingiva
Humans
Microscopy, Atomic Force
Myofibroblasts
Phenotype
Pyruvaldehyde

Source

Open in PubMed

Identifiers

PMID: 28517972
DOI: 10.1902/jop.2017.160730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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