Article
Preparation of Extracellular Matrices Produced by Cultured and Primary Fibroblasts.
Current protocols in cell biology - 1 Jun 2016
Franco-Barraza Janusz, Beacham Dorothy A, Amatangelo Michael D, Cukierman Edna
Abstract excerpt
Fibroblasts secrete and organize extracellular matrix (ECM), which provides structural support for their adhesion, migration, and tissue organization, besides regulating cellular functions such as growth and survival. Cell-to-matrix interactions are vital for vertebrate development. Disorders in these processes have been associated with fibrosis, developmental malformations, cancer, and other diseases. This unit...
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