Article
Antigenic variation in hemagglutinin-neuraminidase of Newcastle disease virus isolated from Tibet, China.
Veterinary microbiology - 1 Oct 2023
Chang Zhengwu, Dong Xiaoyu, Guan Zhao, Lu Kejia, Chen Xi, Wei Xi, Guo Hanwei, Dang Ruyi, Wang Juan, Wang Xinglong, Xiao Sa, Yang Zengqi, Liu Haijin
Abstract excerpt
Vaccines are widely used to prevent Newcastle disease virus (NDV). Under the pressure of immunization, NDVs with mutations among epitopes of F and HN protein were isolated, which indicates that the efficiency of vaccine may decrease in terms of preventing emerged NDV. However, the lack of evidences to support whether these mutations contribute to antigenic mutation and immune escape in NDV leading to the...
Topics
- Animals
- Newcastle disease virus
- Newcastle Disease
- Hemagglutinins
- Neuraminidase
- Tibet
- HN Protein
- Viral Vaccines
- Chickens
- Viral Proteins
- Antibodies, Neutralizing