Article
A population-specific HTR2B stop codon predisposes to severe impulsivity.
Nature - 23 Dec 2010
Bevilacqua Laura, Doly Stéphane, Kaprio Jaakko, Yuan Qiaoping, Tikkanen Roope, Paunio Tiina, Zhou Zhifeng, Wedenoja Juho, Maroteaux Luc, Diaz Silvina, Belmer Arnaud, Hodgkinson Colin A, Dell'osso Liliana, Suvisaari Jaana, Coccaro Emil, Rose Richard J, Peltonen Leena, Virkkunen Matti, Goldman David
Abstract excerpt
Impulsivity, describing action without foresight, is an important feature of several psychiatric diseases, suicidality and violent behaviour. The complex origins of impulsivity hinder identification of the genes influencing it and the diseases with which it is associated. Here we perform exon-foc...
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