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Mitochondrial DNA 4401A>G and 4435A>G Mutations Associated with Essential Hypertension Testing Method.

Clinical laboratory - 1 Jan 2015

Xue Ling, Yu Han, Geng Junwei, Tang Xiaowen

Abstract excerpt

BACKGROUND: Establish a method to identify simultaneously mitochondrial DNA 4401A>G and 4435A>G mutations associated with essential hypertension. METHODS: The whole genomic DNA of samples carrying mitochondrial DNA 4401A>G and 4435A>G mutations, double mutation (mtDNA 4401A>G and 4435A>G) as well as wild type were used as templates. Specifically amplified mtDNA 234 bp fragments between 4344 - 4577 using nested...

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Identifiers

PMID: 26118198
DOI: 10.7754/clin.lab.2015.150111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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