Article
Mitochondrial genome mutations in 13 subunits of respiratory chain complexes in Chinese Han and Mongolian hypertensive individuals.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Oct 2018
Zhao Ying, Chen Xi, Li Haide, Zhu Chao, Li Yang, Liu Yuqi
Abstract excerpt
Mitochondrial DNA (mtDNA) mutations are associated with cardiovascular disease, including hypertension (HTN). Here we performed a genetic and molecular analysis of 13 mtDNA-encoded subunits of respiratory chain complexes in 100 Chinese Han and 80 Mongolian HTN cases, and 100 Han and 42 Mongolian normotension subjects. The total cholesterol of the Mongolian normotensive subjects was higher than that of the Han...
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