Article
Second-line anti-tuberculosis drug resistance and its genetic determinants in multidrug-resistant Mycobacterium tuberculosis clinical isolates.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Jun 2016
Bakuła Zofia, Napiórkowska Agnieszka, Kamiński Michał, Augustynowicz-Kopeć Ewa, Zwolska Zofia, Bielecki Jacek, Jagielski Tomasz
Abstract excerpt
BACKGROUND: Mutations in several genetic loci have been implicated in the development of resistance to second-line anti-tuberculosis (TB) drugs (SLDs). The purpose of this study was to investigate the prevalence of resistance to SLDs and its association with specific mutations in multidrug-resistant (MDR) Mycobacterium tuberculosis clinical isolates. MATERIALS AND METHODS: The study included 46 MDR-TB isolates....
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