Article
Prospects for T. cruzi lineage-specific serological surveillance of wild mammals.
Acta tropica - 1 Nov 2015
Bhattacharyya Tapan, Mills Emily A, Jansen Ana Maria, Miles Michael A
Abstract excerpt
Sequence diversity in the Trypanosoma cruzi small surface molecule TSSA has yielded antigens for serology to investigate the T. cruzi lineage-specific infection history of patients with Chagas disease. Synthetic peptides can be used as the lineage-specific antigens. Here we consider the rationale, feasibility and potential of applying peptide-based lineage-specific serology to naturally infected wild mammals. The...
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