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Article

Distinct requirements for Wntless in habenular development.

Developmental biology - 15 Oct 2015

Kuan Yung-Shu, Roberson Sara, Akitake Courtney M, Fortuno Lea, Gamse Joshua, Moens Cecilia, Halpern Marnie E

Abstract excerpt

Secreted Wnt proteins play pivotal roles in development, including regulation of cell proliferation, differentiation, progenitor maintenance and tissue patterning. The transmembrane protein Wntless (Wls) is necessary for secretion of most Wnts and essential for effective Wnt signaling. During a mutagenesis screen to identify genes important for development of the habenular nuclei in the dorsal forebrain, we...

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Identifiers

PMID: 26116173
DOI: 10.1016/j.ydbio.2015.06.006
PMCID: PMC4639407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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