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Article

APOE ε4 and lipid levels affect risk of recurrent nonlobar intracerebral hemorrhage.

Neurology - 28 Jul 2015

Raffeld Miriam R, Biffi Alessandro, Battey Thomas W K, Ayres Alison M, Viswanathan Anand, Greenberg Steven M, Rosand Jonathan, Anderson Christopher D

Abstract excerpt

OBJECTIVE: Genetic variants ε2/ε4 within the APOE gene are established risk factors for lobar intracerebral hemorrhage (ICH). Published preliminary data suggest a potential role for APOE ε4 in risk of nonlobar ICH. We therefore investigated the role of APOE in recurrent nonlobar ICH, and sought to clarify whether effects of APOE on circulating lipids mediate this association. METHODS: Three hundred sixty-three...

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Source

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Identifiers

PMID: 26115730
DOI: 10.1212/WNL.0000000000001790
PMCID: PMC4520812

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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