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Article

Apolipoprotein E, statins, and risk of intracerebral hemorrhage.

Stroke - 1 Nov 2013

Woo Daniel, Deka Ranjan, Falcone Guido J, Flaherty Matthew L, Haverbusch Mary, Martini Sharyl R, Greenberg Steven M, Ayres Alison M, Sauerbeck Laura, Kissela Brett M, Kleindorfer Dawn O, Moomaw Charles J, Anderson Christopher D, Broderick Joseph P, Rosand Jonathan, Langefeld Carl D, Woo Jessica G

Abstract excerpt

BACKGROUND AND PURPOSE: Apolipoprotein E (ApoE) genotypes have been associated with lobar intracerebral hemorrhage (ICH). Although statins have been associated with an increased risk of ICH, meta-analyses have not consistently shown a statin-induced risk of ICH. Here, we test whether hypercholesterolemia (HC) and ApoE polymorphisms affect the risk of ICH by statin use. METHODS: The Genetic and Environmental Risk...

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Identifiers

PMID: 24008570
DOI: 10.1161/STROKEAHA.113.001304
PMCID: PMC3873717

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