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Article

Apolipoprotein E genotype and the risk of recurrent lobar intracerebral hemorrhage.

The New England journal of medicine - 27 Jan 2000

O'Donnell H C, Rosand J, Knudsen K A, Furie K L, Segal A Z, Chiu R I, Ikeda D, Greenberg S M

Abstract excerpt

BACKGROUND: Recurrent lobar intracerebral hemorrhage is the hallmark of cerebral amyloid angiopathy. The factors that predispose patients to early recurrence of lobar hemorrhage are unknown. One candidate is the apolipoprotein E gene, since both the epsilon2 and the epsilon4 alleles of apolipoprotein E appear to be associated with the severity of amyloid angiopathy. METHODS: We performed a prospective,...

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Identifiers

PMID: 10648765
DOI: 10.1056/NEJM200001273420403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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