Article
ALDH1L1 variant rs2276724 and mRNA expression predict post-operative clinical outcomes and are associated with TP53 expression in HBV-related hepatocellular carcinoma.
Oncology reports - 1 Sept 2017
Zhu Guangzhi, Liao Xiwen, Han Chuangye, Liu Xiaoguang, Yu Long, Qin Wei, Lu Sicong, Su Hao, Chen Zhiwei, Liu Zhengtao, Liang Yu, Huang Jianlu, Yu Tingdong, Yang Chengkun, Huang Ketuan, Shang Liming, Ye Xinping, Li Lequn, Qin Xue, Xiao Kaiyin, Peng Minhao, Peng Tao
Abstract excerpt
Aldehyde dehydrogenase 1 family member L1 (ALDH1L1) is downregulated in hepatocellular carcinoma (HCC) tumors, and its decreased expression is associated with the poor prognosis of HCC patients. We, therefore, evaluated the effect of single nucleotide polymorphisms (SNPs) of ALDH1L1, and its mRNA expression on the survival of hepatitis B virus (HBV)‑related HCC patients and the association with tumor protein p53...
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